The number (%) of joints with radiographic progression
| Joint space narrowing (JSN) | No change in JSN, n (%) | Mild JSN progression* n (%) | Moderate/large JSN progression† n (%) |
|---|---|---|---|
| Baseline JSN=0 | 237 (90.5) | 20 (7.6) | 5 (1.9) |
| Baseline JSN=1 | 104 (71.7) | 31 (21.4) | 10 (6.9) |
| Baseline JSN=2 | 80 (78.8) | 20 (20.0) | 0 (0.0) |
| Total | 421 (83.0) | 71 (14.0) | 15 (3.0) |
| Kellgren–Lawrence grade (KLG) | No change in KLG, n (%) | Mild KLG progression* n (%) | Moderate/large KLG progression† n (%) |
| Baseline KLG=0 | 90 (73.2) | 21 (17.1) | 12 (9.7) |
| Baseline KLG=1 | 38 (59.4) | 20 (31.3) | 6 (9.4) |
| Baseline KLG=2 | 165 (80.9) | 32 (15.7) | 7 (3.4) |
| Baseline KLG=3 | 85 (79.4) | 22 (20.6) | 0 (0.0) |
| Total | 378 (75.9) | 95 (19.1) | 25 (5.0) |
*Mild progression: one grade increase (eg, from KLG=1 to KLG=2).
†Moderate progression: two grades increase (eg, from KLG=1 to KLG=3). Large progression: three grades increase (eg, from KLG=1 to KLG=4).