Table 2

Associations of surrogates for mechanical stress with different types of OA (individuals without OA served as reference)

OR (95% CI)
Knee OAKnee and hand OAHand OA
SDAdjusted*Adjusted incl. metabolic factors†Adjusted*Adjusted incl. metabolic factors†Adjusted*Adjusted incl. metabolic factors†
Weight (kg)15.951.55 (1.39 to 1.73)1.49 (1.32 to 1.68)1.52 (1.31 to 1.76)1.51 (1.29 to 1.78)1.25 (1.09 to 1.42)1.12 (0.96 to 1.32)
Fat-free mass (kg)11.682.33 (1.83 to 2.96)2.05 (1.60 to 2.62)2.29 (1.63 to 3.22)2.17 (1.52 to 3.10)1.43 (1.06 to 1.93)1.17 (0.83 to 1.63)
Fat mass (kg)9.971.43 (1.30 to 1.57)1.37 (1.24 to 1.52)1.42 (1.25 to 1.61)1.41 (1.22 to 1.63)1.21 (1.09 to 1.35)1.11 (0.97 to 1.27)
  • Results are based on weighted analyses of the study population.

  • All ORs express the risk of OA per SD of the independent variable.

  • *Adjusted for age, sex, height, smoking, education, ethnicity.

  • †Adjusted for age, sex, height, smoking, education, ethnicity, metabolic syndrome, hypertension, hyperglycaemia, hypertriglyceridaemia, low high density lipoprotein cholesterol.

  • OA, osteoarthritis.