Logistic regression models of ERAP2 (rs2248374) association controlling for the AS-associated ERAP1 haplotypes (tagged by rs30187 and rs10050860) in HLA-B27-positive cases and either HLA-B27-positive or unselected controls
| Model | Controls | rs2248374 G allele β | SE | OR (95% CI) | p Value |
|---|---|---|---|---|---|
| rs2248374+rs30187+rs10050860+1st 4 eigenvectors | HLA-B27 positive | −0.16 | 0.047 | 0.85 (0.78 to 0.93) | 6.03×10−4 |
| rs2248374+rs30187+rs10050860+1st 4 eigenvectors | Unselected | −0.13 | 0.021 | 0.88 (0.85 to 0.92) | 3.54×10−9 |
| rs2248374+1st 4 eigenvectors | HLA-B27 positive | −0.041 | 0.044 | 0.96 (0.88 to 1.05) | 0.36 |
| rs2248374+1st 4 eigenvectors | Unselected | −0.028 | 0.020 | 0.97 (0.93 to 1.01) | 0.16 |
AS, ankylosing spondylitis.