Table 4

Renal response of pure membranous lupus nephritis

Baseline2 months4 months6 monthsp Value
Urine P/Cr ratio
 p Value*0.440.160.650.52
CrCl (mL/min)
 p Value*0.570.760.030.04
Renal response at 6 monthsMMF (N=12)TAC (N=16)Difference (95% CI)†p Value
CR6 (50%)9 (56%)6% (−27% to 38%)0.09
PR3 (25%)7 (44%)19% (−16% to 47%)
NR3 (25%)0 (0%)−25% (−53% to 0.2%)
  • *p Value (comparison between MMF and TAC, with adjustment of baseline values by analysis of covariance at time points 2, 4 and 6 months).†With reference to MMF.CR, complete response; CrCl, creatinine clearance; MMF, mycophenolate mofetil; NR, no response; P, (comparison between month 6 values with baseline); P/Cr, protein to creatinine; PR, partial response; TAC, tacrolimus.