Table 2

Difference in Western Ontario and McMaster Universities Arthritis Index (WOMAC) outcomes between high-dose and low-dose fish oil at 1 and 2 years, respectively

	Intention-to-treat				Per protocol
	High dose—low dose				High dose—low dose
	1 year (n=101)		2 years (n=101)		1 year (n=80)		2 years (n=65)
Outcome	Mean (SE)	p Value	Mean (SE)	p Value	Mean (SE)	p Value	Mean (SE)	p Value
WOMAC Pain	2.3 (1.2)	0.06	3.3 (1.3)	0.009	3.3 (1.2)	0.007	4.1 (1.2)	0.001
Gender adjusted	2.1 (1.2)	0.081	3.1 (1.3)	0.014	3.1 (1.2)	0.009	4.0 (1.2)	0.001
WOMAC function	6.5 (3.7)	0.08	8.5 (4.0)	0.032	8.4 (3.6)	0.019	11.6 (3.7)	0.002
Gender adjusted	5.9 (3.7)	0.11	7.9 (4.0)	0.046	8.0 (3.6)	0.026	11.2 (3.7)	0.003