Difference in Western Ontario and McMaster Universities Arthritis Index (WOMAC) outcomes between high-dose and low-dose fish oil at 1 and 2 years, respectively
Intention-to-treat | Per protocol | |||||||
---|---|---|---|---|---|---|---|---|
High dose—low dose | High dose—low dose | |||||||
1 year (n=101) | 2 years (n=101) | 1 year (n=80) | 2 years (n=65) | |||||
Outcome | Mean (SE) | p Value | Mean (SE) | p Value | Mean (SE) | p Value | Mean (SE) | p Value |
WOMAC Pain | 2.3 (1.2) | 0.06 | 3.3 (1.3) | 0.009 | 3.3 (1.2) | 0.007 | 4.1 (1.2) | 0.001 |
Gender adjusted | 2.1 (1.2) | 0.081 | 3.1 (1.3) | 0.014 | 3.1 (1.2) | 0.009 | 4.0 (1.2) | 0.001 |
WOMAC function | 6.5 (3.7) | 0.08 | 8.5 (4.0) | 0.032 | 8.4 (3.6) | 0.019 | 11.6 (3.7) | 0.002 |
Gender adjusted | 5.9 (3.7) | 0.11 | 7.9 (4.0) | 0.046 | 8.0 (3.6) | 0.026 | 11.2 (3.7) | 0.003 |