Table 1

Baseline demographics and clinical characteristics

Baseline characteristics
Sex, n (%) female67 (91)
Age, mean (SD) years67.9 (5.3)
Body Mass Index, mean (SD)(n=63)26.4 (3.8)
Fulfilling ACR criteria for hand OA, n (%)69 (93)
AUSCAN pain, mean (SD) (0–20 scale)(n=72)8.0 (3.9)
AUSCAN physical function, mean (SD) (0–36 scale)15.6 (8.0)
Grip strength dominant hand, mean (SD) kilograms(n=68)21 (8.1)
Radiographic findings (presented at joint level)*
Radiographic hand OA (Kellgren–Lawrence)(n=592 joints in 74 participants) n (%)
 Grade 0123 (20.8)
 Grade 164 (10.8)
 Grade 2204 (34.5)
 Grade 3107 (18.1)
 Grade 4†94 (15.9)
Radiographic joint space narrowing(n=592 joints in 74 participants) n (%)
 Grade 0262 (44.3)
 Grade 1145 (24.5)
 Grade 2100 (16.9)
 Grade 3†85 (14.4)
Radiographic erosions(n=536 joints in 67 women) n (%)
 Non-erosive438 (81.7)
 Erosive†98 (18.3)
MRI findings (presented at joint level)‡ (%)
 Synovitis, n (n=511 in 65 patients)346 (67.7)
 Flexor tenosynovitis, n (n=494 in 65 patients)96 (19.4)
 Focal erosions, n (n=579 in 73 patients)290 (50.1)
 Subchondral bone attrition, n (n=579 in 73 patients)113 (19.5)
 Cysts, n (n=579 in 73 patients)24 (4.1)
 Osteophytes (grades 2–3), n (n=582 in 73 patients)185 (31.8)
 Joint space narrowing, n (n=582 in 73 patients)404 (69.4)
 Bone marrow lesions, n (n=591 in 74 patients)73 (12.4)
 Malalignment, n (n=583 in 73 patients)38 (6.5)
 Collateral ligament discontinuity, n (n=582 in 73 patients)327 (56.2)
  • *Eight joints (2nd–5th distal and proximal interphalangeal joints (n=8) in the dominant hand) for each of the n=74 participants (n=67 women in the analyses on erosive evolution).

  • †Excluded from the Generalised Estimating Equation analyses.

  • ‡Eight joints (2nd–5th distal and proximal interphalangeal joints (n=8) in the dominant hand) for each of the n=74 participants (n=67 women in the analyses on erosive evolution). Missing information for certain MRI features if the joint was not completely covered by the field of view, severe deformities and/or no T1-weighted pre-Gadolinium or post-Gadolinium sequence.

  • ACR, American College of Rheumatology; AUSCAN, Australian/Canadian hand index; OA, osteoarthritis.