Table 1

Mean drug levels and antidrug antibodies at baseline

Outcome at 18 monthsMean drug level at baseline mg/L (SD)Antidrug antibodies n (%, 95% CI)
(A) Adalimumab
 Successfully stopped (n=11)8.5 (2.8)ns0 (0, 0 to 26)
 Successfully dose reduced (n=15)8.1 (5.2)1 (7, 1 to 30)
 No dose reduction possible (n=16)6.8 (4.1)3 (19, 7 to 43)
(B) Etanercept
 Successfully stopped (n=11)2.7 (1.3)ns0 (0, 0 to 26)
 Successfully dose reduced (n=37)2.0 (0.9)0 (0, 0 to 9)
 No dose reduction possible (n=28)2.4 (1.0)0 (0, 0 to 12)