Recommendation 10: summary of studies evaluating different localisations to perform dual-energy X-ray absorptiometry in patients with axial spondyloarthritis
| (A) | Radiographic damage (syndesmophytes/BASRI spine) | ||
|---|---|---|---|
| Study | No. | Results in favour of | |
| N=11 | AP/PA spine | Hip | |
| Devogelaer et al137 | 70 | X | |
| Karberg 2005138 | 103 | X | |
| Jun 2006140 | 68 | ND | ND |
| Mullaji 1994142 | 33 | X | |
| Gilgil 2005145 | 20 | X | |
| Muntean 2011147 | 44 | X | |
| Taylan 2012148 | 55 | X | |
| Vasdev 2001151 | 80 | ND | ND |
| Baek 2005154 | 76 | X | |
| Capaci 2003155 | 73 | X | |
| Donelly 1994156 | 87 | X | |
| N=2 | AP/PA spine | Lateral spine | |
| Gilgil 2005145 | 20 | X | |
| Klingberg 2012157 | 204 | X | |
| (B) | Disease duration | ||
|---|---|---|---|
| Study | No. | Correlation between BMD and disease duration | |
| N=12 | AP/PA spine | Hip | |
| Arends 2011170 | 198 | r=0.34 | NS |
| El Magahroui 1999173 | 80 | r=0.23 | NS |
| Gilgil 2005145 | 20 | r=0.52 | NS |
| Grazio 2012158 | 80 | r=0.05 | r=−0.361 |
| Jansen et al133 | 50 | No | r=0.35 |
| Meirelles 1999141 | 30 | r=0.65 | NS |
| Mermerci 2010146 | 100 | r=0.25 | r=−0.20 |
| Muntean 2011147 | 44 | NS | NS |
| Speden et al135 | 66 | NS | NS |
| Taylan 2012148 | 55 | r=0.30 | NS |
| van der Weijden 2011160 | 130 | NS | NS |
| Vasdev 2011151 | 80 | NS | NS |
| N=2 | AP/PA spine | Lateral spine | |
| Gilgil 2005145 | 20 | r=0.52 | NS |
| Memerci 2010146 | 100 | r=0.25 | NS |
| (C) | Disease activity | ||
|---|---|---|---|
| Study | No. | Correlation between BMD and disease activity parameters (ASDAS, BASDAI, CRP, ESR) | |
| N=9 | AP/PA spine | Hip | |
| Frediani et al134 | 186 | NS | NS |
| Grazio 2012158 | 80 | r=−0.30 | r=−0.22 |
| Mermerci 2010146 | 100 | r=−0.24 | r=−0.24 |
| Mullaji 1994142 | 33 | NS | NS |
| Muntean 2011147 | 44 | NS | NS |
| Park 2008159 | 35 | NS | r=−0.49 |
| Taylan 2012148 | 55 | NS | NS |
| van der Weijden 2011160 | 130 | NS | NS |
| Vasdev 2011151 | 80 | NS | NS |
| N=1 | AP/PA spine | Lateral spine | |
| Mermerci 2010146 | 100 | r=−0.24 | r=−0.30 |
The Pearson test for rank correlation is used for test of correlation, values are correlation coefficients (r).
AP, anterior–posterior; ASDAS, Ankylosing Spondylitis Disease Activity Score; BASDAI, Bath Ankylosing Spondylitis Disease Activity Score; BASRI, Bath Ankylosing Spondylitis Radiology Index; BMD, bone mineral density; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; ND, no statistically significant differences; NS, not statistically significant; PA, posterior–anterior.