Performance Improvement of DUET algorithm using different variables | ||||||
---|---|---|---|---|---|---|
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Positive LR | Negative LR | |
HLA B 27+ | 90 | 74.5 | 72 | 92 | 3.55 | 0.12 |
Backache | 95 | 51 | 58 | 94 | 1.93 | 0.09 |
HLA B 27+ and backache | 90 | 95 | 92.6 | 93.3 | 17.79 | 0.10 |
Backache (age of onset <45 years) and HLA B 27+ | 90 | 98 | 97 | 93.5 | 53.38 | 0.09 |
Test algorithm | 100 | 54 | 61 | 100 | 2.18 | 0.00 |
DUET algorithm | 95 | 98 | 97.5 | 96.6 | 56.19 | 0.04 |
AAU, acute anterior uveitis; NPV, negative predictive value; PPV, positive predictive value; LR, likelihood ratio.