Effect of anti-SSA and/or anti-SSB status on each phenotypic feature of SS*
| Phenotypic feature of SS (dependent variables for models 1–6) | Anti-SSA and anti-SSB vs anti-SSA alone | p Value | Anti-SSA alone vs absence of both anti-SSA and anti-SSB | p Value | Anti-SSB alone vs absence of both anti-SSA and anti-SSB | p Value |
|---|---|---|---|---|---|---|
| 1. FS ≥1 vs FS <1 or no FLS | 4.5 (3.4 to 5.9) | <0.0001 | 4.3 (3.5 to 5.3) | <0.0001 | 1.4 (0.8 to 2.4) | 0.2 |
| 2. OSS≥3 vs <3 | 4.2 (2.8 to 6.3) | <0.0001 | 2.0 (1.5 to 2.5) | <0.0001 | 0.9 (0.5 to 1.4) | 0.5 |
| 3. Schirmer ≤5 mm/5 min vs<5 mm/5min | 1.8 (1.4 to 2.3) | <0.0001 | 1.7 (1.3 to 2.1) | <0.0001 | 0.7 (0.4 to 1.3) | 0.3 |
| 4. UWSF<0.1 mL/min vs ≥0.1 mL/min | 2.2 (1.7 to 2.8) | <0.0001 | 1.5 (1.2 to 1.8) | <0.0001 | 0.7 (0.4 to 1.1) | 0.1 |
| 5. RF (+ vs −) | 6.1 (4.7 to 7.9) | <0.0001 | 3.2 (2.6 to 4.0) | <0.0001 | 0.7 (0.4 to 1.5) | 0.4 |
| 6. IgG>14.45 g/L vs ≤14.45 g/L | 5.6 (4.2 to 7.3) | <0.0001 | 4.1 (3.2 to 5.2) | <0.0001 | 0.7 (0.3 to 1.7) | 0.4 |
*Values are ORs and 95% CIs estimated using logistic regression models (1–6) that were adjusted for age, gender and ethnicity.
FLS, focal lymphocytic sialadenitis; FS, focus score; IgG, immunoglobulin G; OSS, ocular surface staining score; RF, rheumatoid factor; SSA, Sjögren's syndrome A; SSB, Sjögren's syndrome B; UWSF, unstimulated whole saliva flow rate.