| Patient characteristics | FIRST Bio | PMS7901 |
|---|---|---|
| Mean disease duration (SD), years | 7.5 (8.9) | 10.4 (9.2) |
| % of patients (pts) whose Steinbrocker's stage was I or II | 60.3 | 35.2 |
| % of pts whose Steinbrocker's class was 1 or 2 | 81.0 | 73.8 |
| % of pts with prior use of biologics | 0 | 62.8 |
| Comparing safety and effectiveness | FIRST Bio at Wk 24 | PMS7901 at Wk 28 |
| Boolean remission rate, % | 27.8 | 15.1 |
| Incidence rate of AEs (serious AEs)* | 75.7 (18.1) | 168.6 (27.4) |
| Incidence rate of infections (serious infections)*, | 17.8 (5.8) | 27.9 (8.6) |
↵* Events/100 patient-years.