TableĀ 3

Multivariable analyses of the association between the number of flares and damage accrual in the case- crossover design*

VariableOR (95% CI); p value
I. Number of flares2.05 (1.43 to 2.94); p<0.001
II. Number of mild-moderate flares1.91 (1.28 to 2.83); p=0.001
Number of severe flares2.62 (1.31 to 5.24); p=0.006
  • *Adjustment variables: length of the intervals, disease duration, adjusted mean SLEDAI, cumulative dose of prednisone, use of antimalarials, use of immunosuppressive drugs and calendar time.