Effect of disease duration on the risk of cardiovascular disease; results of the Cox proportional hazards model with disease duration until event or censoring as the time variable
Variable | Estimate | SE | Exp (B) | p Value | 95% CI | |
---|---|---|---|---|---|---|
Lower | Upper | |||||
Sex (male) | 0.618 | 0.173 | 1.856 | <0.001 | 1.322 | 2.604 |
Age (years) | 0.049 | 0.008 | 1.051 | <0.001 | 1.035 | 1.067 |
Smoking (Y/N) | 0.424 | 0.174 | 1.528 | 0.015 | 1.087 | 2.149 |
BMI (weight (kg)/height (m)2) | 0.065 | 0.018 | 1.067 | <0.001 | 1.030 | 1.105 |
HDL-c (mmol/L) | −0.664 | 0.211 | 0.515 | 0.002 | 0.340 | 0.912 |
Diabetes (Y/N) | 1.050 | 0.312 | 2.857 | 0.001 | 1.549 | 5.268 |
Time-averaged DAS28 | 0.430 | 0.081 | 1.537 | <0.001 | 1.312 | 1.802 |
Biological ever (Y/N) | −0.538 | 0.227 | 0.584 | 0.018 | 0.374 | 0.912 |
MTX ever | −0.336 | 0.187 | 0.715 | 0.072 | 0.496 | 1.031 |
Cox proportional hazards regression model with disease duration until event or censoring as the time variable. Corrected for the confounders shown.
BMI, body mass index; DAS28, 28 joint disease activity score; HDL-c, high-density lipoprotein cholesterol; MTX, methotrexate.