Results for structural outcomes: intent to treat analysis (N=125 for BMLs and N=106 for synovial tissue)*
| Variable | No brace | Brace | Between groups difference | |
|---|---|---|---|---|
| Mean at follow-up, when controlling for baseline value (95% CI) | Mean at follow-up, when controlling for baseline value (95% CI) | Brace/no brace difference (95% CI) | p Value | |
| Primary outcome: patellofemoral BML volume (mm3) | 2709.4 (2426.1 to 2992.8) | 2218.8 (1849.7 to 2588.0) | −490.6 (−929.5 to −51.7) | 0.03 |
| Control outcome: tibiofemoral BML volume (mm3) | 2453.1 (2053.9 to 2852.3) | 2399.3 (1989.6 to 2808.9) | −53.9 (−625.9 to 518.2) | 0.85 |
| Secondary outcome: synovial tissue volume (mm3) | 29 783.0 (28 517.3 to 31 048.8) | 28 096.9 (26 088.4 to 30 105.4) | −1686.1 (−4066.8 to 694.5) | 0.16 |
*This includes knees with no BMLs in the region at baseline.
BML, bone marrow lesion.