Effect of disease activity on the risk of cardiovascular disease; results of the Cox proportional hazards model
| Variable | Estimate | SE | Exp (B) | p Value | 95% CI | |
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Crude model | ||||||
| Time-averaged DAS28 | 0.271 | 0.073 | 1.311 | <0.001 | 1.135 | 1.514 |
| Adjusted model | ||||||
| Time-averaged DAS28 | 0.281 | 0.092 | 1.325 | 0.002 | 1.106 | 1.588 |
| Sex (male) | 0.675 | 0.173 | 1.964 | <0.001 | 1.399 | 2.759 |
| Age (years) | 0.047 | 0.008 | 1.048 | <0.001 | 1.033 | 1.065 |
| BMI (weight (kg)/height (m)²) | 0.090 | 0.013 | 1.094 | <0.001 | 1.066 | 1.123 |
| RF (positive) | 0.300 | 0.224 | 1.349 | 0.182 | 0.869 | 2.095 |
| DAS28 at baseline | 0.114 | 0.073 | 1.120 | 0.118 | 0.971 | 1.292 |
| Biological ever (Y/N) | −0.609 | 0.217 | 0.544 | 0.005 | 0.355 | 0.832 |
Results shown of the Cox proportional hazards regression analysis for the crude model without correction for confounders and for the adjusted model that is corrected for the confounders shown.
BMI, body mass index; DAS28, 28 joint disease activity score; RF, rheumatoid factor; MTX, methotrexate.