Table 1

Outcome of main variables for patients with persistent moderate disease activity (group 1) or sustained DAS28 remission (group 2) during the 5 years of follow-up

BaselineYear 1Year 2Year 3Year 4Year 5
Group 1
 DAS285.3±1.14.0±0.53.7±1.33.5±1.33.2±1.23.0±1.2
 SDAI30.2±12.716.5±6.114.9±12.913.7±11.911.6±10.210.4±9.6
 SJC7.2±4.62.9±3.12.3±3.82.0±2.81.9±3.31.5±2.4
 TJC9.8±6.45.5±4.15.3±6.65.2±7.03.6±4.83.3±4.9
 HAQ-DI1.1±0.70.8±0.60.7±0.60.7±0.60.6±0.60.6±0.6
 ESR (mm/h)30.2±29.418.0±13.317.2±14.017.3±15.416.0±12.916.1±13.4
 CRP (mg/L)19.4±32.68.0±8.27.9±16.47.6±12.110.0±21.27.7±12.0
 mTSS5.5±7.49.8±9.513.6±13.216.1±14.9//
Group 2
 DAS284.5±1.31.7±0.62.0±1.11.9±1.02.0±1.11.9±0.9
 SDAI23.1±13.93.0±2.95.0±6.94.4±5.15.4±8.54.3±5.4
 SJC6.2±5.30.4±1.10.4±0.90.5±1.21.0±3.60.4±0.9
 TJC5.6±5.70.2±0.80.8±2.20.8±1.71.2±3.70.8±2.2
 HAQ-DI0.8±0.70.2±0.30.2±0.40.2±0.30.2±0.40.2±0.4
 ESR (mm/h)25.8±22.48.9±6.110.8±9.110.6±10.210.6±11.110.6±10.3
 CRP (mg/L)21.0±42.94.1±4.76.1±13.14.6±7.04.6±6.55.3±8.0
 mTSS4.5±6.96.3±6.9*8.2±9.5**11.2±11.8***//
  • *p=0.001 versus group 1; **p=0.0005 versus group 1; ***p=0.019 versus group 1.

  • CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; ESR, erythrocyte sedimentation rate; HAQ-DI, Health Assessment Questionnaire-Disability Index; mTSS, van der Heijde modified total Sharp score; SDAI, Simplified Disease Activity Index; SJC, swollen joint count; TJC, tender joint count.