Main thrombotic manifestations related to APS associated with SLE and primary APS that appeared during the 10-year follow-up (1999–2009) of the ‘Euro-Phospholipid’ cohort
| Thrombotic manifestations* | APS associated with SLE (n=132)† No. (%) | Primary APS (n=420)† No. (%) | p Value‡ |
|---|---|---|---|
| Superficial thrombophlebitis | 0 | 8 (1.9) | 0.036 |
| Deep vein thrombosis | 4 (3.0) | 18 (4.3) | |
| Stroke | 9 (6.8) | 20 (4.8) | |
| Transient ischaemic attacks | 8 (3.1) | 13 (3.1) | |
| Myocardial infarction | 5 (3.8) | 5 (1.2) | 0.050 |
| Unstable angina | 4 (3.0) | 10 (2.4) | |
| Pulmonary embolism | 4 (3.0) | 9 (2.1) | |
| Glomerular thrombosis | 4 (3.0) | 1 (0.2) | 0.003 |
*Some patients had several associated presenting manifestations.
†Number of patients that continued in the study until 2009 (230 patients with APS associated with SLE were lost).
‡Pearson χ2.
APS, antiphospholipid syndrome; SLE, systemic lupus erythematosus.