Baseline participant characteristics
| Participant characteristics | N=2126 subjects, 4266 knees |
|---|---|
| Age, mean (SD) | 68 (8) |
| Female, N (%) | 1297 (61) |
| BMI, mean (SD) | 30.8 (5.9) |
| Caucasian, N (%) | 1812 (85) |
| Depressive symptoms, N (%) | 237 (11) |
| Widespread pain, N (%) | 864 (41) |
| Radiographic whole knee OA, N (%) | |
| Knees | 2319 [55] (375 knees replaced) |
| Subjects | 1391 [65] (276 with ≥1 knee replaced) |
| Maximal WOMAC pain, N (knees) [%] | |
| None | 1551 (36) |
| Mild | 1348 (32) |
| Moderate | 909 (21) |
| Severe/extreme | 452 (11) |
| PPT range, kg/cm2 | |
| Patella, median (IQR) | 4.7 (3.4–6.3) |
| Wrist, median (IQR) | 3.1 (2.4–4.1) |
| Temporal summation, N (%) | 877 (41) |
BMI, body mass index; OA, osteoarthritis; PPT, pressure pain threshold; WOMAC, Western Ontario McMaster Universities Osteoarthritis Index.