Table 2

Detailed autoantibody status of patients with overlap syndromes, compared to patients with lcSSc/dcSSc

 SSc subsetsp Values
Overlap s. (n=325)lcSSc (n=1598)dcSSc (n=997)Overlap versus lcSScOverlap versus dcSSc
Autoantibodies%md%md%md 
ANAs positive92.03.187.94.189.14.10.0500.240
ACA positive15.45.253.87.68.48.90.00010.001
ATA positive13.24.916.07.952.48.00.1550.0001
Other Abs68.04.326.76.931.17.20.00010.0001
Other Abs than ACA & ATA, including(n=221)(n=426)(n=310)
 PmScl16.75.92.60.00010.0001
 anti-U1RNP33.05.43.90.00010.0001
 Jo-14.10.51.90.0010.183
 Ku3.60.52.30.0060.601
 Ro24.423.527.70.7700.484
 La10.910.614.20.8940.294
  • md, missing data; missing data were less than 10%.

  • Abs, antibodies; ACA, anticentromer antibodies; ATA, antitopoisomerase antibodies; ANAs, antinuclear autoantibodies.