Table 2

Incidence rate of cardiovascular death, MI, stroke and MACE

CV deathPYIncidence rate per 1000 PYMIPYIncidence rate per 1000 PYStrokePYIncidence rate per 1000 PYMACEPYIncidence rate per 1000 PY
Unexposed902427 5542.1838415 5472.01010419 5732.42055408 5195.0
PsA
 All8645 8891.912344 4962.811945 0372.624943 7105.7
 No DMARD5723 1492.57022 3393.17322 6433.214821 8826.8
 DMARD2922 7401.35322 1582.44622 3942.110121 8294.6
RA
 All1258224 3365.61032212 9044.81094216 8065.02504206 26412.1
 No DMARD67296 6627.040991 7824.556992 9526.1119888 49413.5
 DMARD586127 6744.6623121 1225.1525123 8544.21306117 77011.1
Psoriasis
 All1695744 2572.31643721 7082.31810729 4702.53864708 5545.5
 No DMARD1 645725 4932.31, 603703 6522.31753711 1872.53749690 9315.4
 DMARD5018 7642.74518 0562.55718 2833.111517 6236.5
  • For comparison, according to UK National Statistics between 2000 and 2009, the incidence of MI for men of all ages was 2.05–3.34/1000 and for women of all ages was 0.84–1.52/1000. The incidence of stroke for men of all ages was 1.78–2.77/1000 and for women of all ages was 1.39–2.08/1000.44

  • DMARD, disease-modifying anti-rheumatic drug; MACE, major adverse cardiovascular events; MI, myocardial infarction; PY, person years; RA, rheumatoid arthritis; PsA, psoriatic arthritis.