Development of new syndesmophytes over time
| No of new syndesmophytes | All intervals with at least 1 uninvolved VC* (n (%)) (n=468) | All intervals with at least 1 uninvolved VC* in ‘12 year completers’† (n (%)) (n=240) | First 2 year interval (Y0–Y2) with at least 1 uninvolved VC* (n (%)) (n=153) | |||
|---|---|---|---|---|---|---|
| Reader 1 | Reader 2 | Reader 1 | Reader 2 | Reader 1 | Reader 2 | |
| 0 | 292 (62) | 286 (61) | 141 (59) | 141 (59) | 109 (71) | 102 (67) |
| 1 | 75 (16) | 95 (20) | 48 (20) | 48 (20) | 16 (10) | 23 (15) |
| 2 | 56 (12) | 52 (11) | 25 (10) | 28 (12) | 19 (12) | 18 (12) |
| 3 | 23 (5) | 15 (3) | 12 (5) | 9 (4) | 4 (3) | 5 (3) |
| 4 | 10 (2) | 9 (2) | 5 (2) | 6 (3) | 2(1) | 2 (1) |
| 5 | 4 (1) | 4 (1) | 2 (1) | 2 (1) | 2 (1) | 2 (1) |
| 6 | 2 (0) | 2 (0) | 2 (1) | 1 (0) | 0 (0) | 0 (0) |
| 7 | 1 (0) | 2 (0) | 1 (0) | 2 (1) | 0 (0) | 0 (0) |
| 8 | 3 (1) | 2 (0) | 2 (1) | 2 (1) | 0 (0) | 0 (0) |
| 12 | 0 (0) | 1 (0) | 0 (0) | 1 (0) | 0 (0) | 1 (1) |
| 13 | 1 (0) | 0 (0) | 1 (0) | 0 (0) | 1 (1) | 0 (0) |
| 14 | 1 (0) | 0 (0) | 1 (0) | 0 (0) | 0 (0) | 0 (0) |
| All patients with at least 1 uninvolved VC (n (%)) (n=173) | All patients with at least 1 uninvolved VC and with mSASSS available at Y12 (n (%) (n=62) | First 2 year interval (Y0–Y2) with at least 1 uninvolved VC* (n (%)) (n=153) | ||||
| Reader 1 | Reader 2 | Reader 1 | Reader 1 | Reader 1 | Reader 2 | |
| No of patients with new syndesmophytes | 96 (55) | 109 (63) | 43 (69) | 46 (74) | 44 (29) | 51 (33) |
*Uninvolved VC is a VC without a previous syndesmophyte or bridge, at risk for developing a new syndesmophyte, according to both readers.
†Patients with mSASSS at year 12 available.
mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; VC, vertebral corner.