Table 3

Average direct and indirect annual costs (in €), age 18–64 years, and average direct annual costs (in €), age ≥65 years; calculated with current prices

	2002	2003	2004	2005	2006	2007	2008	2009	2010	2011
Age 18–64 years
Cases (n)	2088	2169	2172	1585	1621	1614	1508	1368	1549	1631
Drugs	2522	3576	3631	4018	4368	4572	4890	5971	6142	6089
Biologic DMARDs	1491	2578	2662	3217	3524	3560	3938	4890	5013	5089
Synthetic DMARDs	661	626	584	431	483	619	598	656	710	608
Other antirheumatic drugs	369	371	386	371	362	393	354	425	420	392
Hospitalisation	1429	1293	1487	1070	984	1142	1411	1145	1230	1237
Rehabilitation	330	299	261	223	178	157	195	186	196	223
Other treatment costs	633	594	598	642	671	601	505	473	624	657
Physician visits	330	314	323	330	336	341	351	221	349	351
Joint replacement surgery	168	149	141	197	227	160	73	161	171	189
Physiotherapy	86	84	86	64	60	50	33	44	55	61
Imaging	48	47	48	50	48	49	48	47	49	55
Total direct costs	4914	5762	5978	5953	6201	6471	7001	7775	8191	8206
Sick leave	1707	1499	2301	1423	1249	1149	1529	1195	1252	1525
Friction cost approach
Permanent work disability	1680	1311	1449	1455	1383	1421	1416	1562	1569	1552
Total indirect costs	3388	2810	3750	2878	2632	2570	2946	2757	2821	3077
Total costs	8302	8572	9728	8831	8833	9041	9947	10 532	11 012	11 283
Human capital approach
Permanent work disability	8902	8017	8712	8551	8013	8064	7902	8566	8459	8229
Total indirect costs	10 609	9515	11 013	9974	9262	9213	9432	9761	9711	9754
Total costs	15 523	15 277	16 991	15 927	15 463	15 684	16 433	17 536	17 902	17 960
Age ≥65 years
Cases (n)	1511	1688	1847	1316	1551	1687	1600	1590	1871	1696
Drugs	1765	2500	2548	2412	2687	2975	3349	3904	3767	4047
Biologic DMARDs	767	1517	1584	1648	1902	2066	2403	2947	2737	3032
Synthetic DMARDs	601	572	538	380	412	532	575	532	590	583
Other antirheumatic drugs	397	411	426	384	374	376	371	425	440	432
Hospitalisation	1447	1392	1353	1439	1115	1238	1281	1201	1304	1126
Rehabilitation	251	230	185	153	148	151	144	153	168	143
Other treatment costs	637	626	638	842	827	699	687	861	840	904
Physician visits	323	307	322	353	361	362	367	349	376	378
Joint replacement surgery	188	198	193	352	337	241	243	419	361	417
Physiotherapy	79	75	76	84	76	43	30	45	52	61
Imaging	48	46	47	53	53	53	47	48	50	48
Total (direct) costs	4100	4748	4724	4846	4777	5063	5462	6120	6079	6221

DMARD, disease modifying antirheumatic drugs.