TableĀ 3

Major groups of genetic variants in the different age groups of patients with TRAPS

Whole TRAPS populationPaediatric patientsAdults with paediatric onsetAdults with adult onset
Number (%)Number (%)Number (%)Number (%)
Sequence variants involving a cysteine residue or T50M58 (37)14 (26)26 (37)8 (23)
Other sequence variants41 (26)12 (23)19 (27)10 (29)
R92Q or P46L59 (37)27 (51)15 (21)17 (49)
Total number of patients (% of total)158 (100)53 (34)70 (44)35 (22)