Cross-sectional associations between leptin and cartilage thickness
| Unadjusted | Multivariable* | |
|---|---|---|
| β (95% CI) | β (95% CI) | |
| Femoral cartilage | −0.018 (−0.024 to −0.012) | −0.013 (−0.022 to −0.003) |
| Medial tibial cartilage | −0.014 (−0.018 to −0.009) | −0.009 (−0.018 to −0.001) |
| Lateral tibial cartilage | −0.019 (−0.025 to −0.013) | −0.012 (−0.021 to −0.003) |
| Patellar cartilage | −0.023 (−0.031 to −0.015) | −0.014 (−0.026 to −0.002) |
Dependent variable: mean cartilage thickness (mm) in respective compartment. Independent variable: serum level of leptin (μg/L).
*Adjusted for age, sex, BMI, radiographic OA, lean mass and having smoked. Data in bold denote statistically significant results.
BMI, body mass index; OA, osteoarthritis.