Table 4

Effect of remission according to different definitions of remission on all-cause mortality

Remission 1
HR (95% CI)*HR (95% CI)†
Ever in remission0.73 (0.56 to 0.94)0.72 (0.55 to 0.94)
Remission score0.86 (0.74 to 0.99)0.85 (0.73 to 0.99)
Time to first remission
 1 year0.68 (0.46 to 0.98)0.65 (0.60 to 0.71)
 2 years0.61 (0.40 to 0.91)0.56 (0.51 to 0.61)
 3 years0.95 (0.65 to 1.40)1.03 (0.95 to 1.12)
  • Remission 1: swollen joint count on 51+tender joint count on 51=0.

  • *Adjusted for age and gender.

  • †Adjusted for age, gender, smoke, RF, previous and/or concurrent treatment with DMARDs, symptoms duration at baseline, swollen joints at baseline, CRP levels at baseline, HAQ at baseline and calendar year; based on multiple imputation of missing data.

  • CRP, C reactive protein; DMARD, disease modifying antirheumatic drug; HAQ, Health Assessment Questionnaire; RF, rheumatoid factor.