Cox proportional hazard regression analysis for the risk of rheumatoid arthritis-associated DVT and PE with interaction of comorbidity
| Variables | n | Event n | Adjusted HR† (95% CI) | p Value‡ | |
|---|---|---|---|---|---|
| DVT | |||||
| Rheumatoid arthritis | Comorbidity | 0.04* | |||
| No | No | 102 311 | 173 | 1 (Reference) | |
| No | Yes | 14 641 | 82 | 2.37 (1.80 to 3.11)** | |
| Yes | No | 24 348 | 143 | 3.69 (2.96 to 4.61)** | |
| Yes | Yes | 4890 | 65 | 6.24 (4.66 to 8.36)** | |
| PE | |||||
| Rheumatoid arthritis | Comorbidity | 0.02* | |||
| No | No | 102 311 | 81 | 1 (Reference) | |
| No | Yes | 14 641 | 58 | 3.15 (2.21 to 4.50)** | |
| Yes | No | 24 348 | 46 | 2.56 (1.78 to 3.68)** | |
| Yes | Yes | 4890 | 24 | 4.45 (2.80 to 7.07)** | |
*p<0.05, **p<0.001.
†Adjusted HR: Adjusted for age and sex.
‡p Value for interaction.
DVT, deep vein thrombosis; PE, pulmonary embolism.