TableĀ 2

Estimated accuracy and diagnostic certainty in detecting ILD on reduced HRCT scans

Reader 1Reader 2
Sensitivity (95% CI)88.3% (78.5% to 94.2%)88.3% (78.5% to 94.2%)
Specificity (95% CI)94.6% (87.3% to 98.0%)100% (95.1% to 100%)
Accuracy91.8%94.7%
NPV (95% CI)90.7% (82.7% to 95.4%)91.2% (83.5% to 95.6%)
High diagnostic confidence*98.8%95.3%
  • *Degree of confidence score 1 or 2 (i.e. 1=fully confident; 2=probably confident).

  • HRCT, high-resolution CT; ILD, interstitial lung disease; NPV, negative predictive value.