Table 4

Ordinal multivariable logistic regression demonstrating adjusted associations between baseline BMI category and risk of higher quintile of bone oedema score in GO-BEFORE at baseline

VariableModel 1*
Risk of higher bone oedema
(N=313)
Model 2 (synovitis in model)*
Risk of higher bone oedema
(N=295)
OR* (95% CI)p ValueOR* (95% CI)p Value
BMI category
 Overweight (25–29.9 kg/m2)0.68 (0.42 to 1.08)0.10.60 (0.35 to 0.94)0.04
 Obese (≥30 kg/m2)0.47 (0.27 to 0.82)0.0080.53 (0.29 to 0.96)0.04
Caucasian0.48 (0.31 to 0.73)0.0010.52 (0.33 to 0.82)0.005
CCP positive1.51 (0.95 to 2.41)0.082.05(1.24 to 3.39)0.005
Disease duration (per 1 year)1.12 (1.07 to 1.18)<0.0011.13 (1.07 to 1.18)<0.001
DAS28(CRP) (per 1 unit)1.32 (1.10 to 1.59)0.0030.96 (0.77 to 1.19)0.7
Synovitis score (per 1 unit)1.24 (1.18 to 1.31)<0.001
  • *Also adjusted for age and sex (non-significant, p>0.2). Tested but not included in final model (p>0.2): corticosteroid use at baseline, active smoking.

  • BMI, body mass index; CCP, cyclic citrullinated peptide; CRP, C-reactive protein; DAS28, disease activity score 28.