Table 2

Cardiovascular parameters in patients with JDM median 16.8 years after disease onset with active and inactive disease and controls

JDM patients
CharacteristicsActive (33)Inactive (26)Total (59)Controls (59)
Age (years)24.2 (6.7–55.4)26.5 (7.8–48.9)21.5 (6.7–55.4)21.6 (6.2–55.4)
Disease duration (years)15.9 (2.0–38.1)18.0 (4.8–34.6)16.8 (2.0–38.1)NA
BP systolic (mm Hg)120 (25.3)114 (17.6)117 (22)111 (13.6)
BP diastolic (mm Hg)71 (15.4)68 (10.2)70 (13.3)67 (9.3)
Septum diastole (mm)7.7 (1.9)8.2 (1.4)7.9 (1.7)7.8 (1.5)
LV diastole (mm)46.6 (5.5)50.0 (4.8)***48.1 (5.5)49.5 (5.9)
LV systole (mm)29.8 (4.5)33.9 (4.3)****31.6 (4.8)32.8 (4.7)*
PW diastole (mm)7.9 (1.9)8.7 (1.2)8.3 (1.6)7.9 (1.4)
LV length (mm)87.1 (9.8)92.2 (8.7)89 (9.6)90.6 (10.4)
EF (%)†64.9 (4.9)63.9 (6.7)63.2 (5.1)62.5 (5.5)
MA displacement (mm)14.5 (1.9)14.7 (1.9)14.6 (1.9)16.0 (1.7)**
Long-axis strain (%)16.9 (2.7)16.1 (2.3)16.6 (2.5)17.7 (2.0)**
e′ (cm/s)‡11.1 (2.8)11.5 (2.7)11.3 (2.8)12.4 (2.1)*
E/e′ ratio‡8.5 (2.3)7.4 (2.1)8.1 (2.3)7.1 (1.2)*
  • Values are median (range) or mean (SD); n=59 pairs except: †; n=47 pairs due to difficulties with data acquisition when measuring EF and ‡; 56 due to missing Doppler data in 3 of the pairs.

  • *p Value<0.05, **p Value≤0.001, when comparing patients and controls.

  • ***p Value<0.05****p Value≤0.001, when comparing patients with active and inactive disease.

  • BP, blood pressure; E, early diastolic transmitral flow; e′, early diastolic tissue velocity; EF, ejection fraction; JDM, juvenile dermatomyositis; LV diastole/systole, left ventricle systolic/diastolic diameter; Long-axis strain, MA displacement as percentage of end-diastolic left ventricular length; MA, mitral annulus; NA, not applicable; PW, posterior wall.