Table 2

List of genes significantly different expressed (≥1.5-fold difference)

Gene symbolAccession nop ValueFold diff.Fnc.Gene symbolAccession nop ValueFold diff.Fnc.
Increased expressionDecreased expression
GPR18NM_001098200.14.31E-082.62RUBE2L3NM_198157.19.26E-121.82E
ZNF564NM_144976.25.22E-081.59TFATF4NM_001675.24.14E-082.07TF
LFNGNM_001040167.11.02E-071.79EH3F3BNM_005324.34.31E-082.19H
ADRB2NM_000024.44.27E-072.23RSNORD68NR_002450.11.54E-071.76O
C16ORF72NM_014117.24.27E-071.70ONFKBIANM_020529.16.02E-061.75TF
PELONM_015946.41.75E-061.65EIRF2BP2NM_182972.27.74E-061.63O
SIAH1NM_001006610.12.64E-061.56EDAB2NM_001343.12.16E-051.68O
HCP5NM_006674.22.78E-061.76OSFRS5NM_006925.32.80E-051.87O
SLANM_001045557.11.90E-051.68OSTK17BNM_004226.23.12E-051.63E
LCMT2NM_014793.31.90E-051.52ECDKN2DNM_079421.24.64E-051.62E
PLAGL2NM_002657.22.18E-051.59TFSFRS17ANM_005088.22.29E-041.55O
FAM43ANM_153690.42.26E-051.92OSFRS5NM_006925.34.61E-041.70O
STK39NM_013233.25.81E-051.56ELOC338799NR_002809.15.02E-041.70O
USP24NM_015306.11.49E-041.67EABCA7NM_019112.35.14E-041.52O
BCDIN3DNM_181708.11.69E-041.51EMAFNM_005360.38.94E-041.66TF
TINF2NM_012461.11.83E-041.54OHS.333764BG1948951.18E-032.51O
PLEKHF1NM_024310.42.67E-041.78EFLJ45337NM_207465.11.29E-031.76O
AP3M1NM_207012.22.79E-041.53OHS.578214DA9576481.45E-031.63O
TM2D3NM_078474.23.11E-041.53OHIST2H2BENM_003528.22.38E-031.80H
CX3CR1NM_001337.34.18E-041.71RMAXNM_145113.12.40E-031.52TF
ZNF217NM_006526.25.83E-041.53TFUSP36NM_025090.24.60E-031.54E
PVRIGNM_024070.36.48E-041.53RLOC644422XR_019449.14.60E-031.67O
PPM1BNM_177968.27.02E-041.68ELEPROTNM_017526.24.80E-031.59O
CASP3NM_032991.28.94E-041.59ESNORD13NR_003041.15.09E-031.96O
SLANM_006748.11.19E-031.65OPPP1R15ANM_014330.25.12E-031.65E
NFE2L2NM_006164.21.40E-031.51TFNBPF10NM_001039703.15.39E-031.81O
ID3NM_002167.21.48E-032.04OACTN1NM_001102.25.54E-031.55O
RABEP1NM_001083585.11.93E-031.75EHS.534061CR6125525.54E-031.63O
KCNJ2NM_000891.22.01E-031.56ONBPF20NM_001037675.15.72E-031.93O
RSBN1NM_018364.34.98E-031.61OOSMNM_020530.36.78E-031.54O
CLK1NM_004071.25.34E-032.26EHIST1H3HNM_003536.27.42E-031.96H
RNMTNM_003799.15.54E-031.59EHIST1H2ACNM_003512.38.64E-031.78H
P2RY13NM_023914.25.54E-031.53RAXUD1NM_033027.28.96E-031.51TF
EBI2NM_004951.35.72E-031.66RVCLNM_003373.31.39E-021.59O
BIRC3NM_001165.38.02E-032.01EEGR1NM_001964.22.13E-025.35TF
EDG1NM_001400.38.83E-031.52RLIMS1NM_004987.32.19E-021.77O
PTPN4NM_002830.21.13E-021.60ETNNC2NM_003279.22.60E-021.56O
HSPA1BNM_005346.31.34E-021.68OIL8NM_000584.22.98E-023.07C
RAB22ANM_020673.21.43E-021.56EMGC13057NM_032321.13.84E-021.64O
ALS2CR13NM_173511.21.61E-021.52OATHL1NM_025092.33.98E-021.81E
PSMC6NM_002806.22.39E-021.52EMMDNM_012329.24.19E-021.55O
FRYLNM_015030.12.53E-021.51OMPLNM_005373.14.19E-021.78R
CSE1LNM_001316.22.68E-021.50RC7ORF41NM_152793.24.97E-021.68O
IL1BNM_000576.22.84E-021.76C
TGFBR3NM_003243.23.41E-021.66R
EBI2NM_004951.33.74E-021.63R
  • C, cytokine; E, enzyme; Fnc., function of the respective gene; Fold diff, fold difference in osteoarthritis patients compared to healthy controls; H, histone protein; O, other; p Value, p values after Bonferroni correction for multiple testing; R, receptor; TF, transcription factor.