Event | Baseline Systemic Steroid Dose Category | PBO + MTX | All CZP Doses |
---|---|---|---|
Incidence rate of AEs/100 pt-yrs | Incidence rate of AEs/100 pt-yrs | ||
Total AEs | None (PBO n=85; CZP n=320) | 276.16 | 242.76 |
≤5 mg/day (PBO n=40; CZP n=204) | 192.88 | 248.23 | |
>5mg/day (PBO n=67; CZP n=246) | 247.15 | 252.81 | |
Total SAEs | None (PBO n=85; CZP n=320) | 2.71 | 13.01 |
≤5 mg/day (PBO n=40; CZP n=204) | 17.34 | 10.81 | |
>5mg/day (PBO n=67; CZP n=246) | 23.15 | 24.91 | |
Serious Infections & Infestations | None (PBO n=85; CZP n=320) | 0 | 3.21 |
≤5 mg/day (PBO n=40; CZP n=204) | 0 | 6.94 | |
>5mg/day (PBO n=67; CZP n=246) | 6.34 | 10.84 |