Table 1. Summary of phosphoproteomic analysis comparing TNFα to 14-3-3η
| # of Targets (%) | Resulting Change | Effect | # of Targets (%) | Representative Phospho/n Targets |
|---|---|---|---|---|
| 19 (76%) | Similar | Increased phosphorylation | 10 (53%) | MEK/ERK, JNK |
| No change | 9 (47%) | PKCα/β | ||
| 6 (24%) | Different | Activation by TNFα | 2 (33%) | p38MAPK & IκBα |
| Activation by 14-3-3η | 2 (33%) | Src |