Features that affect disease severity in patients with childhood familial Mediterranean fever (FMF), obtained through multivariate logistic regression procedures
| Features (reference) | B | OR | 95% CI | p Value |
|---|---|---|---|---|
| Residency (western Europe) | R | |||
| Eastern Mediterranean | 0.932 | 2.539 | 1.371 to 4.703 | 0.003 |
| FMF in the family | ||||
| Absence | R | |||
| Presence | 0.828 | 2.289 | 1.361 to 3.849 | 0.002 |
| Absence of M694 V mutations | R | |||
| M694 V heterozygosity | 0.929 | 2.532 | 1.150 to 5.573 | 0.021 |
| M694 V homozygosity | 1.602 | 4.963 | 2.243 to 10.980 | <0.001 |