Median (IQR) and log transformed percentage increases for endothelial function in the exercise and control groups
| Microvascular dependent Ach | Microvascular independent SNP | Macrovascular dependent FMD | Macrovascular independent GTN | |
|---|---|---|---|---|
| Exercise group | ||||
| baseline | 271.4 (133.3–485.7) | 190.5 (107.8–365.7) | 9.4 (2.2–10.8) | 18.7 (12.9–22.8) |
| 3-months | 394.1 (288.5–600.0) | 423.9 (227.6–608.1) | 18.2 (11.5–24.7) | 24.6 (21.0–30.1) |
| 6-months | 434.1 (244.7–644.7) | 545.8 (303.8–700.1) | 16.7 (12.6–26.7) | 26.1 (19.3–38.7) |
| log baseline | 2.4±0.5 | 2.3±0.4 | 0.8±0.4 | 1.2±0.2 |
| log 3-months | 2.5±0.2 | 2.6±0.3 | 1.2±0.2* | 1.4±0.1** |
| log 6-months | 2.7±0.4* | 2.7±0.2* | 1.2±0.2* | 1.4±0.2 |
| Control group | ||||
| baseline | 331.8 (184.6–454.0) | 318.1 (181.2–531.8) | 7.4 (3.4–14.2) | 20.9 (15.0–28.8) |
| 3-months | 275.9 (155.3–471.6) | 241.7 (139.8–630.8) | 9.9 (3.7–15.5) | 15.0 (12.4–22.9) |
| 6-months | 235.7 (142.9–428.1) | 249.8 (142.9–547.0) | 7.9 (4.1–18.9) | 27.0 (11.4–30.9) |
| log baseline | 2.4±0.2 | 2.4±0.4 | 0.8±0.4 | 1.3±0.2 |
| log 3-months | 2.3±0.4 | 2.5±0.3 | 0.9±0.4 | 1.2±0.2 |
| log 6-months | 2.3±0.4 | 2.5±0.4 | 0.9±0.3 | 1.3±0.3 |
Repeated measures analysis of variance in the log values: significant from baseline * p<0.05 and **p<0.001.
Ach, acetylcholine; FMD, flow-mediated dilatation; GTN, glyceryl trinitrate; SNP, sodium nitroprusside.