Table 3

Synovitis assessed by immunohistochemistry

MarkerSpA (n=8)RA (n=10)CA (n=5)p Value SpA vs RA
CD31.5 (0.0–3.0)0.5 (0.0–1.3)0.5 (0.5–1.3)0.212
CD220.0 (0.0–1.3)0.0 (0.0–0.6)0.0 (0.0–0.75)0.536
CD68 lining2.0 (1.0–2.5)1.5 (1.0–1.9)2.0 (1.0–2.8)0.485
CD68 sublining2.0 (0.5–2.5)0.8 (0.5–1.4)1.5 (1.0–1.8)0.249
CD163 lining1.0 (0.0–2.0)1.0 (0.0–2.0)1.0 (0.5–2.5)0.798
CD163 sublining2.0 (1.0–2.0)1.0 (0.8–1.3)1.0 (1.0–2.0)0.030
von Willebrand factor2.0 (1.0–2.0)1.5 (1.3–2.6)1.5 (1.0–2.0)0.964
  • Values are the median (IQR).

  • Significance of the comparisons is determined by Mann-Whitney U tests. p<0.05 was considered statistically significant. There were no significant differences compared with CA.

  • CA, crystal arthropathy; RA, rheumatoid arthritis; SpA, spondyloarthritis.