Table 1. ACR Paediatric 30 Responses, Week 12

JIA Subtype% Subjects (95% CI)ETN 0.8 mg/kg vs. Placebo Historical Data
ETN 0.8 mg/kgPlacebo Historical dataOdds Ratio (95% CI)
Overall, n=12388.6 (81.6–93.6)28.9 (24.0–34.2)a23.5 (12.5–44.3)
eoJIA, n=5889.7 (78.8–96.1)28.9 (24.0–34.2)a26.2 (10.6–64.2)
ERA, n=3683.3 (67.2–93.6)28.9 (24.0–34.2)a15.1 (6.0–38.2)
ERA, n=3683.3 (67.2–93.6)42.8 (16.9–68.8)b6.7 (1.7–26.3)
PsA, n=2993.1 (77.2–99.2)28.9 (24.0–34.2)a40.7 (9.4–176.9)
  • Modified intent-to-treat (mITT) population (observed cases). aMeta-analysis weighted estimate of placebo response rate in Ruperto et al. [1]. bPlacebo response rate in Burgos-Vargas et al. [2].