Table 1. DCE-MRI parameters and RAMRIS for healthy controls and for early RA patients before and 6 and 12 months after start of DMARD treatment
| Healthy controls | RA Baseline | RA 6 months | RA 12 months | |
|---|---|---|---|---|
| Nvoxel | 3 (0/22) [0/172] | 362 (163/1290)*** | 20 (7/276)* | 23 (6/299)* |
| ME | 1.68 (0/1.80) [0/2.14] | 1.90 (1.80/2.08)** | 1.86 (0.83/1.99) | 1.83 (1.55/2.00) |
| IRE (%/s) | 0.73 (0/1.20) [0/2.20] | 1.65 (1.24/2.48)*** | 1.10 (0.45/1.74) | 1.10 (0.75/1.66) |
| MExNvoxel | 6 (0/44) [0/314] | 669 (304/2760)*** | 38 (11/565) | 42 (11/622) |
| IRExNvoxel (%/s) | 3 (0/28) [0/242] | 607 (196/2438)*** | 82 (7/371)* | 22 (5/548)* |
| RAMRIS synovitis | 0 (0/1.25) [0/3] | 10 (4.75/15.25)*** | 5.5 (4/9.25)*** | 5 (4/11.25)*** |
Median values (25th/75th) [5th/95th] percentiles) for DCE-MRI parameters and RAMRIS are presented. Difference between healthy controls and patients were tested using the Mann-Whitney test,*: p≤0.05; **:p≤0.01; ***:p<0.001.