Table 1

Genotype and clinical characterisation of FMF patient cohort

Case No	MEFV mutation	ESR (mm/1 h)	CRP (mg/dl)	SAA (mg/dl)	Clinical manifestations	Colchicine treatment
1	K695R/K695R	31	4.56	157	Absent	Yes
2	E148Q	<10	<0.46	0	Absent	No
3	M680I/M608I	43	6.15	650	Absent	Yes
4	M694I/M604V	<10	<0.46	0	Absent	Yes
5	E148Q	<10	<0.46	0	Absent	Yes
6	S108R-V726A in cis	<10	<0.46	0	Absent	Yes
7	S108R-V726A in cis	<10	<0.46	0	Absent	No
8	E148Q	<10	<0.46	0	Absent	No
9	M680l-E225G in cis/E148Q	N/A	N/A	N/A	Absent	Yes
10	M680l-E225G in cis	<10	<0.46	0	Absent	Yes
11	M694V/V726A	<10	<0.46	0	Absent	Yes
12	M694V/V726A	<10	<0.46	0	Absent	No
13	M694V/V726A	<10	<0.46	0	Absent	Yes
14	M680l/R761H	<10	<0.46	0	Absent	Yes
15	M694V	<10	<0.46	0	Absent	Yes
16	M694V	N/A	N/A	N/A	Absent	Yes
17	F479L/F479L	<10	<0.46	0	Absent	Yes
18	M694V/M694V	55	9.57	634	Absent	Yes
19	A408Q-P369S in cis	49	2.69	0	Absent	Yes
20	M694V	<10	<0.46	0	Absent	Yes
21	R42W/E230K	23	0.62	50	Absent	No

CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; FMF, familial Mediterranean fever; N/A, not applicable; SAA, serum amyloid A.