Table 1. Percent Goal sUA Attainment at 12 Weeks (mITT)
| Parameter | Allopurinol 300 mg/d | ||||
|---|---|---|---|---|---|
| BXC4208 | |||||
| Placebo | 5 mg/d | 10 mg/d | 20 mg/d | 40 mg/d | |
| Subjects, n | 55 | 56 | 55 | 56 | 53 |
| % Subjects with sUA <6.0 mg/dL | 18% | 45% | 33% | 39% | 49% |
| P value compared with placebo | – | 0.004 | 0.125 | 0.021 | <0.001 |
Overall treatment effect, P=0.009 vs placebo.