Current TherapyChange to TherapyConfirm current TherapyNumber of patientsNotes
IV zoledronateNoYes10BTM confirmed suppression of bone turnover. At 9 months post infusion, subsequent infusions delayed if BTM over suppressed
TeriperatideNoYes9BTM showed increased bone turnover confirming metabolic response at early stage in all patients
RisedronateNoYes1Falling BMD on DEXA but did not meet criteria for teriperatide. BTM confirmed suppression of bone turnover therefore no indication to change to IV zoledronate
AlendronateTeriperatideNo1Falling BMD, new vertebral fracture and meets criteria for teriperatide. BTM suppressed on alendronate therefore changed to teriperatide rather than IV zoledronate
AlendronateDrug HolidayNo1Patient on alendronate for 10 years and BTM over suppressed. After 1 year drug holiday BTM normal and alendronate restarted