Table 2

Locations of observed GIPs

Location of GIPsnbDMARDsAnti-TNFAll
N (%) of GIPsN (%) of deaths*N (%) of GIPsN (%) of deaths*N (%) of GIPsN (%) of deaths*
All GIPs5 (100)3 (60)37 (100)9 (24)42 (100)12 (29)
Upper GIPs3 (60)2 (40)17 (46)3 (8)20 (48)5 (12)
 Oesophagus0 (0)0 (0)2 (5)0 (0)2 (5)0 (0)
 Stomach1 (20)1 (20)5 (14)1 (3)6 (14)2 (5)
 Duodenum1 (20)0 (0)10 (27)2 (5)11 (26)2 (5)
 Gastroduodenal site unspecified1 (20)1 (20)0 (0)0 (0)1 (2)1 (2)
Lower GIPs2 (40)1 (20)20 (54)6 (16)22 (52)7 (17)
 Small bowel1 (20)1 (20)0 (0)0 (0)1 (2)1 (2)
 Appendix0 (0)0 (0)1 (3)0 (0)1 (2)0 (0)
 Diverticula of the colon0 (0)0 (0)9 (24)4 (11)9 (21)4 (10)
 Large bowel (other than diverticula)1 (20)0 (0)5 (14)0 (0)6 (14)0 (0)
 Lower GI tract site unspecified0 (0)0 (0)5 (14)2 (5)5 (12)2 (5)
  • *Death within 30 days after GIP.

  • GI, gastrointestinal; GIP, gastrointestinal perforation.