Table 3

Summary of patients classified as Sjögren's Syndrome by only one set of criteria and not the other

HistologyvB scoreOSSRo/LaANA+RFSchirmer'sWUSFn
AECG criteria only
ACR criteria only
  • The top of the table shows patientss classified under the revised AECG criteria but not under the newly proposed criteria; the bottom shows patients classified as primary Sjögren's Syndrome by the new ACR criteria but not by the modified AECG criteria.

  • Gray shading=the criterion is not evaluated for the corresponding set of criteria: AECG in the top half of the table; ACR in the bottom half.

  • Histology=A positive consists of a focus score ≥1 on minor salivary gland biopsy.

  • vB score=van Bijsterveld Score. AECG scoring system for keratoconjunctivitis sicca; applies only for AECG criteria. It is positive ≥4.24

  • OSS=Ocular Staining Score (lissamine green+fluorescein) for evaluation of keratoconjunctivitis sicca according to the ACR criteria. It is positive ≥3.23

  • Ro/La=A positive consists of the presence of anti-Ro or anti-La in the serum.

  • ANA+RF=Antinuclear antibodies ≥1:320 AND above normal range for laboratory.

  • Schirmer's=Schirmer's I test of tear production with <5 mm in 5 min considered abnormal (+). Does not apply for ACR criteria.

  • WUSF=Whole unstimulated salivary flow with <1.5 mL in 15 min considered abnormal (+). Does not apply for ACR criteria.

  • ACR, American College of Rheumatology; AECG, American–European Consensus Group; RF, rheumatoid factor.