Table 3

Initial genome-wide association studies association results for loci previously reported to be associated with anti-tumour necrosis factor treatment response

SNP	Chr	MAF	Gene	P_GC	β
SNPs from Liu et al18
rs983332	1	0.18	–	0.603	0.031
rs928655	1	0.23	GBP6	0.051	0.109
rs13393173	2	0.19	LASS6	0.71	−0.006
rs437943	4	0.34	–	0.93	0.0006
rs10945919	6	0.32	AKO93144	0.44	0.03
rs854555	7	0.33	PON1	0.61	0.018
rs854548	7	0.25	PON1	0.61	0.0102
rs854547	7	0.35	PON1	0.52	0.0225
rs868856	9	0.31	MOBKL2B	0.65	−0.0218
rs2814707	9	0.26	MOBKL2B	0.95	−0.002
rs3849942	9	0.26	C9orf72	0.98	−0.0069
rs774359	9	0.27	C9orf72	0.89	−0.0159
rs6138150	20	0.18	–	0.66	0.0329
rs6028945	20	0.14	–	0.78	−0.0635
rs6071980	20	0.12	−	0.74	−0.0026
SNPs from Plant et al19
rs12081765	1	0.39	–	0.73	−0.024
rs4694890	4	0.49	TEC	0.4	0.042
rs1532269	5	0.43	PDZD2	0.92	0.051
rs17301249	6	0.18	EYA4	0.36	−0.05
rs1350948	11	0.14	–	0.38	0.0642
rs7305646	12	0.50	–	0.39	0.05
rs7962316	12	0.40	BC118985	0.92	−0.026
SNPs from Krintel et al20
rs10520789	15	0.13	NR2F2	0.47	0.071
rs11870477	17	0.13	MAP2K6	0.67	0.073
rs16973982	15	0.14	NR2F2	0.60	0.072
rs8046065	16	0.10	CREBBP	0.12	0.146
rs885814	1	0.32	ALPL	0.49	0.053
rs869179	1	0.34	ALPL	0.75	0.016
rs2722824	9	0.30	TLR4	0.33	−0.053
rs885813	1	0.43	ALPL	0.30	0.049
rs1875620	9	0.46	C9orf47	0.26	0.051
rs11525966	9	0.45	C9orf47	0.19	0.051
PTPRC
rs10919563	1	0.13	PTPRC	0.384	−0.079

Chr, chromosome; MAF, minor allele frequency; P_GC, p values with genomic control correction applied; SNP, single-nucleotide polymorphisms.