Table 2

Comparison of classification by AECG criteria versus ACR criteria for Sjögren's Syndrome (SS)

AECG criteriaACR criteria*AECG criteria†
SSDNMCTotalEstimated value (95% CI)Estimated value (95% CI)
ACRSS24424268Sensitivity0.87 (0.83 to 0.91)0.91 (0.87 to 0.94)
DNMC35343378Specificity0.93 (0.90 to 0.96)0.91 (0.87 to 0.93)
Total279367646PPV0.91 (0.87 to 0.94)0.87 (0.83 to 0.91)
NPV0.90 (0.87 to 0.93)0.93 (0.90 to 0.96)
  • p=0.19 by Mc Nemar's test; κ=0.81 (95% CIs 0.77 to 0.86).

  • *Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the ACR criteria considering the AECG criteria as the ‘gold standard’.

  • †Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the AECG criteria considering the ACR criteria as the ‘gold standard’.

  • ACR, American College of Rheumatology Criteria Classification Criteria for SS; AECG, American European Consensus Group Classification Criteria for Sjögren's Syndrome; DNMC, did not meet criteria; SS, Sjögren's Syndrome.