Sensitivity and specificity of the 2013 SSc classification criteria and previous SSc classification criteria, overall and in early SSc
| Derivation sample (n=200) | Validation sample (n=405) | Validation sample, disease duration ≤3 years (n=100) | ||||
|---|---|---|---|---|---|---|
| Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | |
| 1980 ACR SSc criteria | 0.80 (0.72 to 0.87) | 0.77 (0.68 to 0.84) | 0.75 (0.70 to 0.80) | 0.72 (0.64 to 0.79) | 0.75 (0.70 to 0.80) | 0.72 (0.63 to 0.79) |
| 2001 LeRoy/Medsger SSc criteria | 0.76 (0.68 to 0.84) | 0.69 (0.68 to 0.84) | 0.75 (0.70 to 0.80) | 0.78 (0.70 to 0.85) | 0.80 (0.69 to 0.88) | 0.76 (0.53 to 0.92) |
| 2013 ACR/EULAR SSc criteria | 0.95 (0.90 to 0.98) | 0.93 (0.86 to 0.97) | 0.91 (0.87 to 0.94) | 0.92 (0.86 to 0.96) | 0.91 (0.83 to 0.96) | 0.90 (0.70 to 0.99) |
ACR, American College of Rheumatology; EULAR, European League Against Rheumatism; SSc, systemic sclerosis.