Table 3

Log-transformed levels of the biomarkers, sCOMP and uCTX2

MarkerControlsHealthy agersp Value*
sCOMP0.97 (0.11) (320)0.99 (0.11) (318)0.018
Male sCOMP0.97 (0.12) (144)0.98 (0.11) (174)0.268
Female sCOMP0.97 (0.11) (176)1.00 (0.12) (144)0.025
uCTX22.35 (0.25) (329)2.36 (0.24) (329)0.359
Male uCTX22.29 (0.22) (148)2.29 (0.22) (179)0.865
Female uCTX22.40 (0.27) (181)2.44 (0.24) (150)0.283
  • Values are mean (SD) (number of valid serum or urine measurements).

  • *p Value when comparing controls and healthy agers adjusted for age, sex and age×sex interactions where applicable.

  • sCOMP, serum cartilage oligomeric protein; uCTX2, urinary cross-linked C-telopeptide of type 2 collagen.