Table 1

Differences in clinical, instrumental and lung ultrasound data between patients with very early SSc and those with SSc

Very early SSc (n=32)SSc (n=26)p Value
Age (years)51±1552±130.72
Female (%)29 (91%)25 (96%)0.62
Disease duration (years)1.9±3.25.9±9.9<0.05
Scl-70 positivity (%)7 (22%)16 (62%)<0.01
FEV1/FVC (%)89±1785±100.36
TLC (%)105±2677±13<0.001
Dlco (%)79±1563±19<0.05
Dlco/Va (%)85±1783±160.68
Ejection fraction (%)65±460±5<0.01
B-lines on anterior chest (n)8±1122±21<0.01
B-lines on posterior chest (n)10±1244±40<0.001
Total number of B-lines (n)18±2166±57<0.001
  • Dlco/Va, diffusing capacity of the lung for carbon monoxide/alveolar volume; FEV1, forced expiratory volume in 1 s; FEV1/FVC, forced expiratory volume in 1 s/forced vital capacity; SSc, systemic sclerosis; TLC, total lung capacity.