Table 3

Association between MRI inflammation and axial pain sites in the DESIR cohort according to radiographic findings at the sacroiliac joints (SIJ) (multivariate analysis)

Thoracic (n=70)Lumbar (n=82)Sacroiliac (n=163)
OR (95% CI)*p ValueOR (95% CI)*p ValueOR (95% CI)*p Value
Normal SIJ radiographs (n=475): Inflammatory lesions at MRI
Thoracic pain1.76 (0.97–3.22)0.061.21 (0.71–2.07)0.470.98 (0.64–1.49)0.92
Lumbar pain1.02 (0.40–2.57)0.973.19 (0.92–11.12)0.071.32 (0.61–2.83)0.48
Buttock pain0.93 (0.50–1.73)0.811.03 (0.56–1.90)0.922.29 (1.36–3.85)0.002
Gender (male)2.06 (1.17–3.63)0.011.93 (1.13–3.28)0.021.97 (1.30–3.00)0.001
Age (+1 SD)1.41 (1.05–1.89)0.021.71 (1.30–2.26)0.00010.93 (0.75–1.14)0.5
HLA-B272.58 (1.42–4.67)0.0021.38 (0.82–2.33)0.221.91 (1.26–2.90)0.002
lnCRP (+1SD)1.24 (0.93–1.66)0.131.10 (0.84–1.42)0.481.06 (0.86–1.29)0.58
Abnormal SIJ radiographs (n=173): inflammatory lesions at MRI
Thoracic (n=55)Lumbar (n=58)Sacroiliac (n=140)
Thoracic pain2.09 (0.97–4.47)0.061.24 (0.62–2.52)0.540.63 (0.26–1.58)0.33
Lumbar pain1.03 (0.28–3.84)0.961.63 (0.42–6.34)0.48NANA
Buttock pain1.44 (0.45–4.56)0.540.37 (0.13–1.06)0.061.74 (0.51–5.94)0.38
Gender (male)5.65 (2.36–13.5)0.00011.57 (0.75–3.28)0.230.91 (0.36–2.31)0.85
Age (+1 SD)1.54 (1.05–2.25)0.031.19 (0.84–1.68)0.330.74 (0.49–1.11)0.15
HLA-B271.51 (0.62–3.66)0.361.27 (0.56–2.88)0.571.75 (0.69–4.46)0.24
lnCRP (+1SD)1.49 (0.92–2.40)0.11.29 (0.84–1.98)0.251.14 (0.72–1.81)0.56
  • CI, confidence interval; CRP, C-reactive protein.

  • Radiographs of the SIJs were classified as abnormal if they showed inflammation or fusion and as normal otherwise.

  • Normal MRIs were defined as MRIs scored 0 and abnormal MRIs as MRIs scored 1 or 2.

  • *ORs estimated using logistic regression models.