Table 2

Association results of the 10 top hits

SNP informationGene informationStage 1Stage 2Stage 1 and 2 (combined)
SNP IDCHRMinor allele (MA)Other allele (OA)MAF (%)Nearest geneDistance to gene (kb)OR (minor allele)95% CIp ValueOR (minor allele)95% CIp ValueOR (minor allele)95% CIp Value
rs133611605ct43.5FAM173B56.71.301.18 to 1.421.18×10−81.060.98 to 1.160.1611.171.10 to 1.244.67×10−7
rs806561017ac38.7PMP2241.91.261.15 to 1.383.86×10−70.930.85 to 1.020.1191.081.02 to 1.161.20×10−2
rs121326741ag29.5HMGCS20.01.281.16 to 1.419.29×10−71.070.97 to 1.170.1651.161.09 to 1.241.23×10−5
rs1160630411gt9.07TPH10.00.550.43 to 0.701.47×10−60.990.81 to 1.220.9340.780.66 to 0.911.64×10−3
rs76803634at6.42PROM10.01.521.28 to 1.801.72×10−61.040.86 to 1.250.6881.271.12 to 1.441.52×10−4
rs48374929ct4.51FREQ56.21.231.13 to 1.342.96×10−60.970.89 to 1.070.5681.101.03 to 1.172.68×10−3
rs52451318tc18.2BRUNOL40.01.291.16 to 1.444.00×10−60.960.85 to 1.090.5371.131.04 to 1.232.75×10−3
rs78359688ga12.7KHDRBS3175.81.341.18 to 1.524.26×10−60.980.86 to 1.120.7871.161.06 to 1.271.43×10−3
rs224910411tc8.8MYOD13.71.421.22 to 1.644.57×10−60.990.84 to 1.170.8821.211.08 to 1.358.78×10−4
rs1779631219ga33.1FBL7.11.241.13 to 1.379.79×10−61.080.97 to 1.20.1661.171.09 to 1.252.56×10−5
  • CHR, chromosome; MA, minor allele or effect allele (minor allele=effect allele); MAF, minor allele frequency (%);OA, other allele.