Table 3

Top hit association results

Type of analysisStage 1Stage 2Stage 1 and 2 (combined)
SNP testedAdjustmentsOR (95% CI)p ValueOR (95% CI)p ValueOR (95% CI)p Value
rs13361160Age, BMI, and 4 PCs1.30 (1.19 to 1.42)1.18×10−81.06 (0.98 to 1.16)0.161.17 (1.10 to 1.24)4.67×10−7
(minor allele=C, other allele=T, MAF=43.5%)
Sensitivity analysis; joint pain only
rs13361160Age, BMI, and 4 PCs1.30 (1.19 to 1.42)1.18×10−81.10 (0.97 to 1.25)0.151.23 (1.14 to 1.32)3.43×10−8
(minor allele=C, other allele=T, MAF=43.5%)
  • In both analyses the effect estimates of the models refer to the minor allele (=effect allele).

  • BMI, body mass index; MAF, minor allele frequency.